CA inhibitor 2 - 搜索结果 | AbMole中文官网

找到约 22 条 “CA inhibitor 2” 相关结果（用时 0.108 秒）

目录号	产品名称	中文名称	靶点
M8775	DMAT	DMAT	Others
	Casein kinase II Inhibitor; CK2 Inhibitor
	Casein kinase II inhibitor II (Ck2 Inhibitor II) is a high affinity ATP-competitive inhibitor of casein kinase II.
M21208	BCATc Inhibitor 2	BCATc Inhibitor 2	Others
	BCATc Inhibitor 2 是一种磺酰肼，可抑制BCATc，对大鼠的IC50s为0.2 µM。它对BCATm有15倍的选择性。它还被用来阻止钙流入神经元，抑制谷氨酸摄取后的IC50为4.8μM，并在体内大鼠神经退行性模型中显示出神经保护的功效。
M42298	CA inhibitor 2	CA inhibitor 2	Carbonic Anhydrase
	CA inhibitor 2 是一种碳酸酐酶抑制剂 (IC50: 0.033 μM)。
M2497	Cathepsin Inhibitor 1	Cathepsin Inhibitor 1	Cathepsin
	Cathepsin Inhibitor 1是一种组织蛋白酶(L，L2，S，K，B)的抑制剂，pIC50分别为7.9，6.7，6.0，5.5，5.2。
M6651	Damnacanthal	丹宁卡；丹拿堪索	Others
	Damnacanthal is a potent, selective p56 ^lck inhibitor; also LIMK1/2 inhibitor.
M7731	CHIC-35	CHIC-35	Others
	CHIC-35 is cell-permeable, metabolically stable, and very potent inhibitor of SIRT1; IC₅₀ of S-isomer is 60 nM; IC₅₀ of mixed isomers is 124 nM.
M7934	MDL 28170	MDL 28170	Gamma-secretase/Beta-secretase
	Calpain Inhibitor III
	MDL-28170 (Calpain Inhibitor III) 是一种有效的、选择性的、具有膜渗透性的半胱氨酸蛋白酶 (calpain)抑制剂，可穿过血脑屏障。MDL-28170 还能阻断γ-secretase。
M8313	CZC-25146 hydrochloride	CZC-25146 hydrochloride	LRRK2
	CZC-25146 is a potent selective and metabolically stable inhibitor of leucine-rich repeat kinase-2 (LRRK2) also known as dardarin or PARK8, a kinase with mutations linked to Parkinson’s disease.
M8747	Synta66	Synta66	Calcium Channel
	Synta66 (S66) is a CRAC (Ca2+ release-activated Ca2+) channel inhibitor that blocks SOCE (store-operated Ca2+ entry) upon Ca2+ depletion from intracellular stores by thapsigargin in human vascular smooth muscle cells (VSMCs) with high potency.
M14303	CPA inhibitor	CPA inhibitor	Others
	Carboxypeptidase inhibitor
	CPA inhibitor (Carboxypeptidase inhibitor; compound 5) 是一种有效的羧肽酶 A (CPA) 抑制剂，Ki 值为 0.32 μM。
M14905	PKA Inhibitor Fragment (6-22) amide TFA	PKA Inhibitor Fragment (6-22) amide TFA	PKA
	PKI-(6-22)-amide TFA
	PKA Inhibitor Fragment (6-22) amide TFA 是 cAMP 依赖性蛋白激酶 A (PKA) 的抑制剂，Ki 值为 2.8 nM。PKA Inhibitor Fragment (6-22) amide TFA 可显着逆转小鼠低水平的吗啡缓解疼痛的感受性。
M20388	AC480 (BMS-599626)	AC480 (BMS-599626)	EGFR/HER2
	AC480 (BMS-599626) is a selective and efficacious inhibitor of HER1 and HER2 with IC50 of 20 nM and 30 nM, ~8-fold less potent to HER4, >100-fold to VEGFR2, c-Kit, Lck, MET etc. Phase 1.
M20458	Tabersonine hydrochloride	Tabersonine hydrochloride	Amyloid
	Tabersonine, an ingredient extracted from the bean of Voacanga africana, is a potent inhibitor against Aβ(1?42) aggregation and toxicity.
M20776	cis-Resveratrol	cis-Resveratrol	Keap1-Nrf2
	cis-RESV, cRes, (Z)-Resveratrol
	cis-Resveratrol (cis-RESV, cRes, (Z)-Resveratrol) is the Cis isomer of Resveratrol. Resveratrol is a natural phenolic compound with anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol is an inhibitor of pregnane X receptor (PXR) and an activator of Nrf2 and SIRT1 and may induce apoptosis.
M20864	L-2-Hydroxyglutaric acid disodium	L-2-Hydroxyglutaric acid disodium	Histone demethylase
	(S)-2-Hydroxyglutaric acid disodium, L-2-Hydroxyglutarate disodium, LGA, L-2HG
	L-2-Hydroxyglutaric acid disodium ((S)-2-Hydroxyglutaric acid disodium, L-2-Hydroxyglutarate disodium, LGA, L-2HG) is an epigenetic modifier and a putative oncometabolite in kidney cancer that inhibits histone demethylases and hence promotes histone methylation. L-2-Hydroxyglutaric acid disodium is also an inhibitor of mitochondrial creatine kinase (Mi-CK) with Km and Ki of 2.52 mM and 11.13 mM, respectively.
M28912	(Rac)-Calpain Inhibitor XII	(Rac)-Calpain Inhibitor XII	Proteasome
	(Rac)-Calpain Inhibitor XII 是可逆的，选择性的钙蛋白酶 I (calpain I; μ-calpain) 抑制剂，Ki 值为 19 nM。(Rac)-Calpain Inhibitor XII 对钙蛋白酶 II (calpain II; m-calpain; Ki=120 nM) 和组织蛋白酶 B (cathepsin B; Ki=750 nM) 具有较低的亲和力。
M29336	CA inhibitor 1	CA inhibitor 1	HIV Protease
	GS-6207 analog
	CA inhibitor 1 (GS-6207 analog) 是一种有效的 HIV 衣壳抑制剂，可用于抑制 HIV。
M30928	ADAMTS-5 Inhibitor	ADAMTS-5 Inhibitor	Others
	ADAMTS-5 Inhibitor 是一种有效的 ADAMTS-5 (aggrecanase-2) 抑制剂，IC50为 1.1 μM。ADAMTS-5 Inhibitor 的功能选择性比 ADAMTS-4 (aggrecanase-2) 高出 40 倍以上。
M42165	Cav 3.2 inhibitor 4	Cav 3.2 inhibitor 4	Calcium Channel
	Cav 3.2 inhibitor 4 是一种有效的外周限制性选择性 T 型钙通道 (Cav3.2) 抑制剂，IC50 值为 0.6 μM。
M42905	Cathepsin Inhibitor 3	Cathepsin Inhibitor 3	Others
	Cathepsin Inhibitor 3 是化合物 [18F]2k 放射性合成中的非放射性中间体，对组织蛋白酶 S 具有选择性。
M52418	Autocamtide-2-related inhibitory peptide, myristoylated	Autocamtide-2-related inhibitory peptide, myristoylated	CaMK
	Autocamtide-2-related inhibitory peptide, myristoylated 是Autocamtide-2-related inhibitory peptide 烷基化修饰后的形式。
M54029	Calcineurin autoinhibitory peptide	Calcineurin autoinhibitory peptide	Phosphatase
	Calcineurin autoinhibitory peptide 是一种选择性的 Ca2+/ 钙调蛋白依赖性蛋白磷酸酶(钙调神经磷酸酶)的抑制剂，IC50 值大约为 10 μM。

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